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Showing posts from December, 2023

Revolution In Treatment of Sickle Cell Anemia: CRISPER Cas9 - Dr Markandaiya Acharya

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Sickle Cell Anemia is a hereditary blood disorder that affects millions of people globally. The traditional treatments for this condition often come with limitations and side effects, prompting researchers to explore innovative solutions. One such groundbreaking technology gaining attention is CRISPR Cas9.  In this article, we delve into the potential of CRISPR Cas9 in revolutionizing the treatment landscape for Sickle Cell Anemia. Understanding Sickle Cell Anemia Genetic Basis Sickle Cell Anemia is caused by a mutation in the HBB gene, leading to the production of abnormal hemoglobin known as hemoglobin S (HbS). Individuals with two copies of the mutated gene (HbS/HbS) develop Sickle Cell Anemia, while those with one normal and one mutated gene (HbA/HbS) are carriers but generally do not exhibit symptoms. Hemoglobin S tends to polymerize under conditions of low oxygen, causing red blood cells to deform and adopt a sickle shape. These sickle cells are less flexible and more prone t...

Demystifying Cellulitis

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Imagine a fit middle-aged man walks into the clinic, limping and visibly distressed. He's a proud traffic policeman but has developed leg swelling and fever in the last few days, making even basic tasks painful. He suspects his job is to blame.  Let's dive into the complexities of this common leg issue to empower you in understanding and managing this common skin issue. What is Cellulitis? Cellulitis is a skin infection caused by bacteria, reaching beyond the surface. It can affect anyone, causing redness, swelling, and pain. The usual suspects are Staphylococcus and Streptococcus bacteria, entering through cuts or insect bites. Symptoms and Diagnosis Early detection of cellulitis symptoms is vital for quick treatment. Look out for: Redness and warmth in affected areas Swelling and tenderness Fever and chills Getting a Professional Diagnosis If you suspect cellulitis, consult a healthcare pro. Diagnosis involves examining symptoms and medical history. Sometimes, blood tests or ...

Unlocking the Secrets of Intermittent Fasting

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In the vast tapestry of human history, the practice of voluntary abstinence from food and drink, commonly known as intermittent fasting, has woven its threads across diverse cultures since ancient times. Ethnological texts and religious scriptures vividly portray the myriad forms of fasting, reflecting a rich tapestry of human traditions. The resurgence of interest in fasting is palpable, evident in the plethora of popular press publications and diet recommendations that inundate the modern world. The Quest for Evidence: Navigating Fasting Regimens The crux of this exploration lies in understanding the diverse intermittent fasting regimens and deciphering the evidence regarding their impact on human health. Three major themes emerge: alternate day fasting, modified fasting regimens, and time-restricted feeding. Alternate Day Fasting This fasting variant involves alternating days of complete abstinence from energy-containing foods with days of unrestricted eating. Studies in rodents sug...