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Cortisol: The Stress Hormone and Your Wellbeing

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In our fast-paced world, it's no surprise the term " cortisol " gets thrown around a lot. On social media, it's often blamed for everything from weight gain to breakouts. But what exactly is cortisol, and can we truly " balance " it for optimal health? ( Cortisol levels fluctuate throughout the day, so doctors may use blood, urine, or saliva samples to measure them.   Pic source: Freepik ) Cortisol: The Body's Built-in Alarm Cortisol is a hormone produced by the adrenal glands, those small glands perched on top of your kidneys. Nicknamed the " stress hormone ," cortisol plays a vital role in the body's fight-or-flight response. When you encounter a stressful situation, cortisol surges, giving your body a much-needed energy boost. It increases blood pressure, releases glucose for fuel, and puts you on high alert.  Our bodies have a natural cortisol rhythm: levels are highest in the morning, gradually dipping throughout the day. This helps us

Promising HIV Vaccine: A Hopeful Step Towards Ending the AIDS Pandemic

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Millions infected annually, a vaccine is crucial to stopping HIV/AIDS.  While vaccines typically train the immune system to fight specific pathogens, HIV's vast variations and the body's struggles to produce effective antibodies have hindered vaccine development for decades. ( Colorized transmission electron micrograph of numerous HIV virus particles (blue) replicating from a T cell (red).  NIAID Integrated Research Facility ) New Hope Emerges: Broadly Neutralizing Antibodies (bnAbs) Over a decade ago, researchers identified a rare type of antibody, called broadly neutralizing antibodies (bnAbs), that could combat numerous HIV strains. These bnAbs have shown promise in preventing infection, but inducing them with a vaccine has proven difficult.  Targeting the Rare: Activating bnAb-Precursor B Cells The key lies in stimulating the rare immune cells that develop into bnAb producers - bnAb-precursor B cells.  A team led by Dr. William Schief at Scripps Research Institute designe

Hope and Heartbreak: The Story of Xenotransplantation and Its Complexities

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Imagine a world where organ shortages are a thing of the past. A world where anyone in need of a life-saving transplant can receive one, regardless of waiting lists or donor availability. This is the promise of xenotransplantation, the transplantation of animal organs into humans.  (Image: Richard Slyman 62 year old recipient of genetically modified pig kidney ) Recent news has been a mixed bag for this developing field. The first recipient of a genetically modified pig kidney, 62-year-old Richard Slayman, passed away two months after the surgery. While the cause of death remains unclear, the event has sparked renewed discussions about the potential and the risks of xenotransplantation. What is Xenotransplantation? Simply put, xenotransplantation is the use of animal cells, tissues, or organs to treat humans. The need for this procedure arises from the severe shortage of donor organs. In the United States alone, nearly 90,000 people wait for a kidney transplant, with thousands dying ea

Don't Let Fatigue Rule Your Life: Taking Control of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

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Living with chronic fatigue feels like being trapped in a permanently exhausted body. Even the simplest tasks leave you drained, and a good night's sleep offers little relief. This is the daily reality for millions battling Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a complex illness that continues to perplex the medical community. (Image Source: National Day Calendar  ) For years, ME/CFS has been shrouded in confusion. There's no single known cause, no definitive test, and treatment options have remained limited. However, a new wave of research is shedding light on this puzzling illness. Studies are revealing a complex interplay between the immune system, nervous system, and hormones that may be a key factor in the debilitating symptoms. The Three Pillars of ME/CFS Imagine ME/CFS as a three-legged stool. This recent review highlights three main systems that seem to be working together to cause the hallmark symptoms of fatigue, pain, and sleep problems: 1. Th

Salt and Stomach Cancer: Should You Ditch the Salt Shaker?

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Let's face it, most of us love a good sprinkling of salt on our food. It enhances flavor and can make a bland dish sing. But a new study from the University of Vienna has some of us rethinking our reach for the salt shaker. Researchers found a 41% increased risk of stomach cancer  in people who frequently added salt to their meals, compared to those who used it sparingly.  (Image Source: Tasting Table  ) This isn't the first time scientists have connected high-salt diets with stomach cancer. Studies in Asia already pointed towards this link. However, this Vienna study is one of the first to solidify this connection in Western populations, including folks like us in the US. ALSO READ:  The Link Between Bacteria and Stomach Cancer & it's not H. pylori: A Breakthrough Study So, how exactly does salt hurt your stomach?   While the current study is observational, previous research suggests excessive salt intake might weaken the protective lining of your stomach. This damage

How to Eat Right to Fight Undernutrition and Obesity?

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India faces a unique challenge - malnutrition in two forms. While a significant portion of children battle undernutrition, there's also a rising trend of overweight and obesity. This " double burden " of malnutrition can be tackled through a simple solution: a healthy diet . (Image Source: The Quint  ) The latest Dietary Guidelines for Indians (DGIs), developed by the Indian Council of Medical Research (ICMR), offer a roadmap for healthy eating. Let's explore what these guidelines recommend and how they can help us fight both undernutrition and obesity. The Problem on Our Plates Our current diet relies heavily on cereals (rice, wheat), often exceeding recommended levels. This leaves little room for other essential food groups like pulses, vegetables, fruits, and nuts. This lack of variety leads to micronutrient deficiencies , like iron and folic acid, causing anemia. At the same time, the easy availability and aggressive marketing of unhealthy, processed foods high

Understanding Kyasanur Forest Disease (KFD): A Lethal Threat in Karnataka

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As Karnataka grapples with the devastating impact of Kyasanur Forest Disease (KFD), also known as monkey fever, the recent death of a five-year-old girl in Udupi district serves as a grim reminder of the urgency to address this viral infection. With the toll rising to nine and cases increasing in Malnad’s districts, including Shivamogga, Uttara Kannada, and Chikkamagaluru, it's evident that immediate action is necessary to contain its spread. Encephalitis Virus or Lyme Borreliosis Disease or Monkey Fever Infectious Dermacentor Tick Arachnid Insect(PICTURE FOR REPRESENTATIONAL PURPOSES ONLY) (Image Source: Hindustan Times) ALSO READ:  Protecting Little Lungs: Understanding and Preventing Toddler Asthma What is KFD, and why is it a cause for concern?  First identified in 1956 in the Kyasanur Forest area of Shivamogga district, KFD gets its name from its place of origin. Spread through ticks, the disease not only affects humans but also poses a threat to primates, serving as a warning